Whether you use your email for business or personal purposes, encrypting it is vital to keeping your communications and sensitive information secure.
Because hackers are so determined and now have the advantage of AI, it’s more of a matter of “when” than “if” they will one day gain access. Explore the best encryption integrations for Microsoft 365 to keep your emails between you and the recipient.
1. DataMotion
DataMotion’s numbers and knowledge speak for themselves. It’s currently active in 2,000 organizations, has 10 million users and has enabled a 23% support reduction and 48% efficiency gains after over two decades in operation.
The company also holds certifications from HITRUST, DirectTrust, the Drummond Group and more, showcasing its commitment to keeping clients’ emails safe across the public, financial and health care sectors.
Users hold DataMotion in high regard for its ease of use and robust integration into Microsoft 365. This solution also offers to lower fragmentation across your Microsoft Cloud with compliant document, email and form exchanges directly within their relevant apps.
Prominent names like Santander, Varian and the Indiana Health Information Exchange trust it to secure their data. Thanks to these assets, certifications and results, DataMotion is one of the best encryption integrations for Microsoft 365.
Key Features
- Intuitive design for fast adoption, seamless integration and user autonomy
- Zero-trust architecture and encryption that align with the strictest requirements
- Scalable to millions of users
- Multiple opportunities to use artificial intelligence (AI) to streamline management
2. OpenText
OpenText knows email theft can lead to compliance issues and reputation damage, so it is ready to protect your communications from bad actors.
It has data-loss prevention (DLP) filters that recognize and secure sensitive text in email attachments, subjects or bodies. The filters can also quarantine or block the message based on rules you give it.
Through DLP filters, OpenText enhances security compliance and improves the client’s posture. The product also enables users to collaborate securely on messages via the Secure Compose portal.
Its overall simple setup and protection for any device, anywhere make OpenText a worthy contender.
Key Features
- Reporting via graphs for compliance audits
- A Best Method of Delivery engine that chooses the safest delivery method, like the Secure Messaging Portal, message-level encryption or Transport Layer Security
- External contacts can initiate encrypted messages
- Customizable and automatic DLP filters that enable automatic encryption for the sender and recipient
3. PreVeil
One of the main benefits PreVeil customers talk about is its affordability. However, that doesn’t mean it skimps on its protective services.
This solution has currently secured 1,800 defense contractors, 20,000 organizations and 100,000 users with Health Insurance Portability and Accountability Act (HIPAA), Payment Card Industry (PCI) and Cybersecurity Maturity Model Certification (CMMC) compliance.
Clients can deploy this solution in under an hour, and they can access their communications via the Apple App Store and Google Play Store.
The end-to-end encryption, zero-trust architecture and promise that no one but the intended recipient can read the email further exemplify PreVeil’s dedication to security.
Key Features
- Encrypted email and file sharing that simplifies compliance with health care, law enforcement, manufacturing, higher education and more regulations
- Affordability and simple activation make access easier
- Protection from server attacks, ransomware, compromised administrators and password theft
- Option for a free account that still enables third-party collaboration
4. Egress Protect
Egress Protect also has a big numbers and names backing it up. It currently serves the world’s largest private health care provider. It is used by over 70% of health care firms, and three-quarters of its customers are legal, government, financial and municipal entities.
Users also benefit from International Standards Organization (ISO) 27001, Commercial Product Assurance and Federal Information Processing Standards 140-2 accreditation.
This solution uses end-to-end encryption, access restrictions, multi-factor authentication, and malware and content protection. Users can also place various restrictions on the messages, such as geolocation, time, and the ability to print, save, forward, copy or paste the text or any attachments.
With the ability to manage those requirements from their mobile devices and adjust them after sending, Egress Protect stands out as one of the best encryption integrations for Microsoft 365.
Key Features
- Emails remain safe in cases of account compromise because Egress Protect is a layer away from Microsoft 365
- Automatic integration into Microsoft Purview Information Protection
- Ability to bypass mail client file size limits
- Visibility into who users are sending sensitive information to and how frequently, top classification labels, supply chain risks, and usage and adoption rates
5. SecureMyEmail
Getting started with SecureMyEmail is free, and it may stay that way, depending on whether you’re using it for consumer or other purposes.
Either way, you won’t need to include any payment information to give it a go, making access quick and easy. Its software also works on Mac, Android, Windows and iOS, so your choice of device won’t pose a problem.
SecureMyEmail will encrypt any current personal or corporate email address as long as the provider supports Internet Message Access Protocol (IMAP), which most do.
Big names like Microsoft have built-in automated setups, and the team is currently working on plugins and additional features for Outlook. The provider ensures end-to-end encryption, user friendliness and assurance that no one can read your encrypted communications.
Key Features
- Ease of use makes setup and implementation quick
- Mobile and desktop access for free and paid accounts
- Scales from individual to large-enterprise use
- HIPAA and General Data Protection Regulation (GDPR) compliance
6. Proofpoint
Proofpoint acknowledges that 65% of data loss occurs through email, 40% of team members email the wrong person and data breaches have an average 30% risk of happening at any time.
To combat this, its DLP engine allows you to define detailed encryption rules and apply them at user, group and global levels. The software can also accurately find sensitive information in Microsoft 365 communications, images, PDFs and more.
With Unified DLP, administrators can use a single interface for configuration, detection and remediation. That kind of operational efficiency can make their jobs much more straightforward and reduce the chances of threats slipping through.
Key Features
- Hundreds of prebuilt data identifiers that enable the DLP engine to spot potentially sensitive data
- Content and behavioral analysis that can halt lateral phishing
- AI models that utilize threat intelligence from over 2.8 trillion annual emails
- Risk summaries for emails that enable them to avoid social engineering
7. Virtru
Virtru has over 6,000 customers trusting it to protect their emails, with big names like Netflix, Salesforce and Brown University on its roster. It has enabled a big four bank that transmits over 700,000 pieces of information daily to decrease its support tickets by 90% and has saved a global engineering firm $1 million.
A broker-dealer trying to comply with regulations from the United States Securities and Exchange Commission was able to raise their delivery rate by 100%.
Virtu’s email encryption provides simple-to-use end-to-end security for existing Microsoft Outlook workflows. Keep the keys in a secure place of your choosing, and use the attribute-based access controls to lock certain information down based on who receives it and when.
You can even automate these granular access policies, helping prevent data loss.
Key Features
- Options for government, enterprise and small businesses
- Encryption that supports CMMC, International Traffic in Arms Regulation (ITAR) and Criminal Justice Information Services (CJIS) compliance
- The choice of self-managing your environment or a fully managed cloud
- Service in sectors from finance to aerospace
A Quick Comparison of the Best Encryption Integrations for Microsoft 365
Compare these Microsoft 365 integrations to see how they stack up.
| Price | AI Features? | Certifications | Auditing Features? | Other Providers It Works With | |
| DataMotion | Contact a representative | Yes | HITRUST Alliance, Office of the National Coordinator for Health Information Technology, Electronic Healthcare Network Accreditation Commission, the Drummond Group, DirectTrust | No | Not listed |
| OpenText | Contact a representative for subscription details | No | Not listed | Yes | On-premises mail server and Gmail |
| PreVeil | Basic service is free, extra storage is $25/month, business plans cost $30/user/month and government clients should contact a representative | No | CMMC, HIPAA, Federal Risk and Authorization Management Program, PCI, ITAR, Federal Information Processing Standard | No | Gmail and Apple Mail |
| Egress Protect | Contact a representative | No | 13, including ISO 27001, PCI, NHS Digital – Data Security and Protection Toolkit, Cyber Essentials Certification, Common Criteria | Yes | Primarily Outlook and can work with Gmail |
| SecureMyEmail | Multiple subscription tiers, with basic single accounts free forever and encrypted and VPN-protected accounts starting at $4.99/month | No | HIPAA and GDPR | No | Any email provider that supports IMAP |
| Proofpoint | Contact a representative | Yes | Not listed | No | Gmail, on-premises mail server and cloud providers |
| Virtru | Contact a representative | No | Not listed | Yes | Gmail |
Finding the Best Encryption Integrations for Microsoft 365 Is Crucial
Email providers don’t always automatically encrypt your communications, so it’s vital to use a tool for it in every industry — someone will likely try to steal your information, whether you’re an individual account or a team member in a large enterprise.
The best encryption integrations for Microsoft 365 help keep those messages amongst the right people, helping you avoid critical security mishaps.

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